A Cadaveric Evaluation of Hypertrophic Obstructive Cardiomyopathy

Hypertrophic obstructive cardiomyopathy (HOCM) describes a pathologic state in which the subaortic region of interventricular septum undergoes significant hypertrophy and fibrosis, resulting septal bowing into left ventricle. The reduced ventricular chamber size altered cardiac function impair diastolic filling, stroke volume, output. This case report evaluates tissue 36-year-old, formalin-embalmed cadaver affected by HOCM, with goal providing comprehensive overview gross findings associated condition. donor’s heart was found to be larger than average, weighing 510.1 g, is 52% heavier predicted value 335.6 g for male similar stature. thickness septum, right free wall, wall comparable other reports HOCM. However, asymmetrical thickening walls, characteristic less prominent expected. Histologic staining cadaveric tissue, hematoxylin eosin, trichrome, desmin, further bolstered diagnosis. Importantly, this also showed that histologic examination embalmed effective diagnostic, even 11 months after embalming. herein demonstrates morphologic analysis sufficient support diagnosis To researchers' knowledge, first evaluating HOCM donated medical education.